Research team identifies differences between benign and pathogenic gene variants

An international team of researchers led by Cleveland Clinic’s Lerner Research Institute has performed for the first time a wide-scale characterization of missense variants from 1,330 disease-associated genes. Published in Proceedings of the National Academy of Sciences, the study identifies features associated with pathogenic and benign variants that reveal the effects of the mutations at […]

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Low quantity and quality of muscle predicts poor outcomes in colon cancer surgery

Low muscle quality and quantity are both predictive of poor outcomes in colon resection surgery, according to a new study published in JAMA Surgery. Carla Prado, a researcher in the University of Alberta’s Faculty of Agricultural, Life & Environmental Sciences, and her team followed 1,630 patients who received a diagnosis of Stage I to Stage […]

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