The 49ers remain way ahead of the Patriots, but they’ve lost another offensive player to injury.
Wide receiver Deebo Samuel has been ruled out with a hamstring injury. Samuel had five catches for 65 yards before leaving the game in the second half.
Samuel’s exit came a short time after running back Jeff Wilson took a cart to the locker room. He’s been ruled out with an ankle injury that cut short a splendid performance. Wilson ran 17 times for 112 yards and three touchdowns.
The 49ers are up 33-6 in the fourth quarter despite those losses and they are now facing Patriots quarterback Jarrett Stidham after New England pulled Cam Newton. Stidham’s first possession ended with an interception.